Asian Cohort for Alzheimer's Disease

Asian Cohort for Alzheimer’s Disease

The Asian Cohort for Alzheimer’s Disease (ACAD) is an international collaboration with the goal of compiling a robust sample size of Asian American and Canadian subjects for Alzheimer’s disease research.

CAN-THUMBS UP

CAN-THUMBS UP

The Canadian Therapeutic Platform Trial for Multidomain Interventions to Prevent Dementia – CAN-THUMBS UP (CTU) is a group of over 100 Canadian researchers within the Canadian Consortium on Neurodegeneration in Aging focused on dementia prevention. The CTU platform was initiated in 2019 and is part of the World Wide FINGERS prevention initiative.

Longitudinal Menopause Project

Longitudinal Menopause Project

The goal of the Longitudinal Menopause Project (LMP) is to generate one of the most detailed examinations of brain health and menopause in the US to date. Recruitment will begin in Fall 2026 for women ages 40–55.

BenfoTeam Study

BenfoTeam Study

The BenfoTeam Study tests if increasing thiamine in the blood slows cognitive decline in people with early Alzheimer’s disease, including Mild Cognitive Impairment (MCI) and mild dementia.

Gene Therapy Program

Gene Therapy Program

The goal of the Epstein Family Alzheimer's Research Collaboration Gene Therapy Program (GTP) is to achieve a successful gene therapy treatment for Alzheimer’s disease in people living with the Jalisco PSEN1 mutation.

Powder for Pennies Program

Powder for Pennies

The Epstein Family Alzheimer's Research Collaboration Powder for Pennies (P4P) Program aims to create a unique incubator and screening platform to test an array of single and combinatorial repurposed medicines and natural products in clinical trials for the treatment and prevention of Alzheimer’s disease.

Virtual Reality Brain Health Study

Virtual Reality Brain Health Study

The Virtual Reality Brain Health Study is a novel study that uses three methods of lifestyle intervention involving physical exercise and Virtual Reality to promote brain health and cognition in older adults.

VIVA-MIND Study


The VIVA-MIND trial is designed to determine if the study drug, varoglutamstat, can stabilize or slow memory and thinking problems that increase in early AD.

PEACE-AD Study

PEACE-AD is a multicenter, randomized, placebo-controlled study evaluating the efficacy and safety of the Prazosin drug.

UC Cures NEAT Study

NEAT is a Phase 2, proof of concept, double-blind, randomized, placebo-controlled adaptive design trial of Nicotinamide in MCI due to AD and Mild AD Dementia.

 

UC Cures SAL-AD Study

SALAD is a Phase 1b, 12-month, randomized, double-blind, placebo-controlled study of the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of salsalate in patients with mild to moderate Alzheimer’s disease. 

DISCOVER Study

The Discover Study is a randomized, double-blind, placebo controlled study. Participants will be treated with a low, middle, or high dose of Posiphen, or a placebo (a capsule that looks like the study drug but does not contain active ingredients).

3 Star Study

The 3 Star Study will research and test whether an investigational vaccine can affect Alzheimer’s disease-related brain changes in participants with Down Syndrome.The 3 Star Study is designed for individuals who have Down Syndrome, are 25-45 years of age, do not have any other serious illness, and have a caregiver or informant who can answer questions about them.

EXERT Study

The EXERT study is a national, 18-month long, clinical trial to test whether physical exercise can slow the progression of mild memory loss and/or mild cognitive impairment in older adults between the ages of 65-89.

T2 Protect AD Study

T2 is designed to determine if troriluzole can protect, slow down, or potentially improve memory and thinking problems that increase as Alzheimer’s disease progresses. 

Huperzine A (HU) Study


A multicenter, double-blind, placebo-controlled therapeutic trial to determine whether natural huperzine A improves cognitive function in Alzheimer’s disease.

NOBLE Study

NOBLE is a clinical study to evaluate an investigational drug for patients with mild to moderate Alzheimer’s disease. The investigational drug may work by protecting brain cells, which could result in improved memory. The study will determine whether the drug is efficacious.

Resveratrol Study

A Phase II clinical study of Resveratrol (RES) designed to evaluate the safety, tolerability and effectiveness of Resveratrol on cerebrospinal fluid and other biomarkers for the treatment of Alzheimer’s disease.

Home-Based Assessments Study

Evaluate three methods of performing home-based assessments in an Alzheimer’s disease prevention trial.

Nerve Growth Factor Study

Ceregene’s CERE-110 gene therapy product designed to deliver nerve growth factor (NGF) to the brain for the treatment of Alzheimer’s disease is currently underway.

ADNI Study

Determine whether imaging of the brain every six months can help predict the onset of Alzheimer’s disease, and monitor the progression of the disease as well.

GAP Study


Further examination of the safety, effectiveness and tolerability of IVIg in mild to moderate Alzheimer’s Disease patients.

Docosahexaenoic Acid Study


A randomized, double-blind, placebo-controlled trial of the effects of Docosahexaenoic Acid (DHA) in slowing the progression of Alzheimer’s disease.

Valproate Neuroprotection Study

Determine whether chronic valproate therapy delays the emergence of agitation and/or psychosis in outpatients with probable Alzheimer’s disease who have not experienced agitation and psychosis in their illness.

Rage Inhibitor Study

The experimental drug in this study may block a critical pathway in Alzheimer’s disease that causes damage to the nerve cells in the brain.